Reference number
ISO/TS 23973:2020
Technical Specification
ISO/TS 23973:2020
Liquid chromatography at critical conditions (LCCC) — Chemical heterogeneity of polyethylene oxides
Edition 1
2020-08
Technical Specification
Read sample
ISO/TS 23973:2020
77489
Published (Edition 1, 2020)
This publication was last reviewed and confirmed in 2024. Therefore this version remains current.

ISO/TS 23973:2020

ISO/TS 23973:2020
77489
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CHF 173
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Abstract

This document establishes a valid method for separation of chemically heterogeneous polyethylene oxide (PEO) mixtures and for the determination the number and content of the chemically heterogeneous species in the overall sample.

The method presented in this document serves as a technical guideline and enables laboratories to learn the principle of "critical chromatography" on a validated system.

This method presented in this document with its stated system parameters is not applicable for other polymer classes, due to the diversity of the interactions between the polymer/mobile phase/stationary phase and the number of separation systems that are therefore available.

The evaluation of the interlaboratory testing has shown that many error sources relate to the technique of liquid chromatography in general. Possible error sources are described in Annex A.

Details on the evaluation of the interlaboratory testing are given in Annex B.

Elugrams of the participants (excerpts) are given in Annex C.

Investigations of the long-term stability of the test mixture are given in Annex D.

General information

  •  : Published
     : 2020-08
    : International Standard confirmed [90.93]
  •  : 1
     : 49
  • ISO/TC 35/SC 16
    71.040.50 
  • RSS updates

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